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ea0063gp191 | Adrenal and Neuroendocrine - Clinical | ECE2019

Pneumocystis pneumonia as a major complication of medical treatment for severe Cushing’s syndrome linked either to ectopic ACTH secretion or to Cushing’s disease

Cristante Justine , Mallaret Michel , Tourvieilhe Laura , Carreau Agnes , Vaillant Tiphaine , Yoldjian Isabelle , Chabre Olivier

Several cases of pneumocystosis developing after lowering cortisol serum level have been reported, mostly in patients with ectopic Cushings syndrome. We report here 2 cases of pneumocystosis which developed after initiation of treatment with metyrapone, one in a patient with Cushings disease, and the second in a patient with ectopic ACTH secretion by a prostate endocrine carcinoma. Both cases presented severe Cushings syndrome. We then analyzed the periodic s...

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Pneumocystis pneumonia as a major complication of medical treatment for severe Cushing’s syndrome linked either to ectopic ACTH secretion or to Cushing’s disease

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